Autophagy - slows down the aging process, protects against certain diseases

Professor Yoshinori Ohsumi, a Japanese cell biologist associated with the Tokyo Institute of Technology, owes groundbreaking research into the self-cleaning process of cells - autophagy. (Greek: autos - sam, phagein - to eat, loosely translated: cell self-eating).
For his discoveries that have practical application in everyday life, he was awarded the Nobel Prize in Medicine and Physiology in 2016.

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What is autophagy?

To put it simply, this process consists in processing by the cell of unnecessary, dead or damaged elements of its structure into prime factors, later used for the production of new organelles as well as energy stored in the form of a compound - ATP.
Cell fragments intended for decomposition, defective proteins, viruses, bacteria and fungi are closed in small vesicles from the cell membrane, which are then transported to the lysosomes. The lysosomes contain enzymes that make it possible to digest proteins. Cellular recycling is more perfect than in everyday life. No waste is left behind. This process occurs in both healthy and diseased cells. Organisms also use it during embryogenesis.

What is the risk of disruption of autophagy processes?

The organism starts to "clean up" when we do not supply enough nutrients from the outside. Conversely, autophagy processes are disrupted and stopped when the body is overfed with an incorrect diet. As the latest research shows, the disturbance of autophagy processes is the cause of metabolic diseases, eg type II diabetes, neurodegenerative diseases, eg Parkinson's disease, neoplastic diseases, fatty liver or diseases of the heart muscle - called cardiomyopathies. Disruption of autophagy processes accelerates the aging of the body

When is autophagy activated?

Autophagy is especially intensified in situations of caloric restriction, at times of starvation of the body. Hence, periodic dietary programs limiting the supply of calories, proteins and fats are so effective in regenerating the body.
Autophagy also increases with intense regular exercise.

When do we use autophagy in therapy?

For example, therapy with the vegetable and fruit program, which strongly activates these cellular recycling processes, turns out to be very effective in arterial hypertension, type II diabetes, insulin resistance, coronary artery disease, arthritis, fertility problems caused by food intolerances, and immune disorders resulting from from an improper diet, in Parkinson's disease, in sarcoidosis and psoriasis and other conditions. It is good to carry out such therapy under the supervision of a doctor.